The composer is Mead Composer-in-Residence at the Chicago Symphony Orchestra. Her music has been performed all over the world by the Kronos Quartet, eighth blackbird, pianist Emanuel Ax, Opera Philadelphia, Scottish Opera, LA Opera, Cincinnati Opera, New York City Opera, Detroit Symphony Orchestra, Los Angeles Philharmonic, Minnesota Orchestra, American Composers Orchestra, and many other eminent soloists and ensembles. In 2018 she made history when she became one of the two first women (along with composer Jeanine Tesori) to be commissioned by the Metropolitan Opera. That year she was also nominated for a Grammy in the category of “Best Classical Composition” for her work Vespers for Violin, recorded by violinist Olivia De Prato. Proving Up, commissioned by Washington National Opera, Opera Omaha and New York’s Miller Theatre, premiered at the Kennedy Center in January 2018. Earlier projects include Mazzoli’s much-acclaimed operas Song from the Uproar (2012) and Breaking the Waves (2016). Mazzoli has also earned renown as a composer for film and television, and she is an active pianist and keyboardist.